Using Temporal Correlation in Factor Analysis for Reconstructing Transcription Factor Activities
نویسندگان
چکیده
منابع مشابه
Using Temporal Correlation in Factor Analysis for Reconstructing Transcription Factor Activities
Two-level gene regulatory networks consist of the transcription factors (TFs) in the top level and their regulated genes in the second level. The expression profiles of the regulated genes are the observed high-throughput data given by experiments such as microarrays. The activity profiles of the TFs are treated as hidden variables as well as the connectivity matrix that indicates the regulator...
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ژورنال
عنوان ژورنال: EURASIP Journal on Bioinformatics and Systems Biology
سال: 2008
ISSN: 1687-4145,1687-4153
DOI: 10.1155/2008/172840